Microphysiological Systems for Dissection of Host - Microbiota Interaction, Disease Modelling and Drug Screening 

Lung-on-chip Publications



Stefanie Deinhardt-Emmer, Sarah Böttcher, Clio Häring, Liane Giebeler, Andreas Henke, Roland Zell, Franziska Hornung, Christian Brandt, Mike Marquet,  Alexander S. Mosig, Mathias W. Pletz, Michael Schacke, Jürgen Rödel, Regine Heller, Sandor Nietzsche, Bettina Löffler, Christina Ehrhardt; SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction, bioRxiv, 2020, doi: https://doi.org/10.1101/2020.08.31.276725

Deinhardt-Emmer S, Rennert K, Schicke E, Cseresnyes Z, Windolph M, Nietzsche S, Heller R, Swiczak F,  Haupt KF, Carlstedt S, Schacke M, Figge MT, Ehrhardt C, Löffler B, Mosig AS; Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model., Biofabrication, 2020, 12(2):025012. Published 2020 Feb 19

Schicke E, Cseresnyés Z, Rennert K, Vau V, Haupt KF, Hornung F, Nietzsche S, Swiczak F, Schmidtke M, Glück B, Koch M, Schacke M, Heller R, Mosig AS, Figge MT, Ehrhardt C, Löffler B, Deinhardt-Emmer S.; Staphylococcus aureus lung infection results in down-regulation of Surfactant Protein-A mainly caused by pro-inflammatory macrophages., Microorganisms, 2020, accepted